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Polyphenols: Phenolic Acids and Alcohols Standard Mixture - V2

Standard mixture solution for chromatography and mass spectrometry

Tags: polyphenols standard mixt, phenolic acids standard mix, phenolic alcohols standard mix, lingnans, tannins


Use: Liquid Chromatography (LC, HPLC, UHPLC) 

Use: Compounds identification, MS2 transitions,  retention time acquisition, in-house digital library, method development


Suitable for:  LCMS, UHPLC, LCMS, LC-MS/MS, LC-QTOF 

Suitable for: Single quadrupole MS, triple quadrupole MS (QQQ), QTOF, Orbitrap

Suitable: Human metabolomics, plant metabolomics, foodomics, food analysis, volatilomics, cannabis and vape analysis, wine and beer analysis, pharmaceutical products




-Find the retention time of the molecules after changing the method
-Find the retention time of molecules after changing the column
-Use the standards to make calibration curves for quantification


HPLC-MS (single qaud):
-Find the retention time of molecules after changing the method
-Add the compounds to your in-house library for enhanced compound search/identification with RT and m/z value


HPLC-MS/MS (triple qaud):
-Acquire and optimize the transition ions for each molecule using your instrument specific settings
-Use the standards to make calibration curves for quantification


-Use the standards to make calibration curves for quantification
-Add the compounds to your in-house library for enhanced search with RT and m/z value


The presence of polyphenolic micronutrients in food is shown to be beneficial to humans health due to their powerful anti-oxidation properties. MetaSci’s Phenolic Acids and Alcohols (PAA) Standard Mix contains 50 phenolic compounds that are building blocks of polyphenols. The standard mixtures come as 0.10 mg/mL DMF solution and are suitable to use with HPLC methods utilizing a standard C18 column and MS, UV or ELSD detector. Each mixture is designed to have 10 compounds highly resolved on C18 column with no isobaric interference which makes it to work even on a low resolution MS. The standard mixtures can be used for peak identification, making calibration curves for quantification and making an in-house digital library of spectra.

  Some of the more volatile polyphenol building blocks (such as phenol, pyrogallol and phlorglucinol) are moved to our Aromatic Volatile Standard Mixtures, because of excessivelylow signal due to volatility and inefficient ionization using ESI ion source.  To cover a larger collection of polyphenols you can use the Aromatic Volatile Standard Mixtures for LCMS methods.


  • 50 phenolic acids and phenolic alcohols, high purity, single peak, completely resolved
  • Fully quantitative, 0.10 mg/mL.
  • 5  High recovery sets with 10 phenolic compound in each. Each set contains five microampules of 200 uL. Using microampules allows you to keep the unused amount in the sealed glass container. Each set contains 5 microampules, totalling to 25 microampules.
  • Packed under argon
  • Contains an internal standard to adjust your retention time with IS lock
  • No isobaric interference means there are no two compounds with the same molecular formula in a microampule. This design allows identification by low resolution single quad mass spectrometer without a need for digital libraries for identification.

Polyphenols: Phenolic Acids and Alcohols Standard Mixture - V2

  • List of compounds

    1. 2,3-Dihydroxybenzoic acid  (HMDB0000397, CAS 303-38-8)
    2. Chlorogenic acid  (HMDB0003164, CAS 327-97-9)
    3. Syringic acid  (HMDB0002085, CAS 530-57-4)
    4. p-Coumaric acid  (HMDB0002035, CAS 7400-08-0)
    5. m-Hydrocoumaric acid  (HMDB0000375, CAS 621-54-5)
    6. Ferrulic acid  (HMDB0000954, CAS 1135-24-6)
    7. Sinapic acid  (HMDB0032616, CAS 530-59-6)
    8. Acetylsalicylic acid  (HMDB0001879, CAS 50-78-2)
    9. p-Anisic acid  (HMDB0001101, CAS 100-09-4)
    10. trans-Cinnamic acid  (HMDB0000930, CAS 140-10-3)
    11. Resorcinol  (HMDB0032037, CAS 108-46-3)
    12. 4-Hydroxybenzoic acid  (HMDB0000500, CAS 99-96-7)
    13. 2,6-Dihydroxybenzoic acid  (HMDB0013676, CAS 303-07-1)
    14. Dihydrocaffeic acid  (HMDB0000423, CAS 1078-61-1)
    15. Caffeic acid  (HMDB0001964, CAS 331-39-5)
    16. Phloretic acid  (HMDB0002199, CAS 501-97-3)
    17. Hydroferulic acid  (HMDB0062121, CAS 1135-23-5)
    18. o-Anisic Acid  (PUBCHEMCID11370, CAS 579-75-9)
    19. Ellagic acid dihydrate  (HMDB0002899, CAS 476-66-4)
    20. 5-methoxysalicylic acid  (HMDB0001868, CAS 2612-02-4)
    21. Catechol  (HMDB0000957, CAS 120-80-9)
    22. Gentisic acid  (HMDB0000152, CAS 490-79-9)
    23. 3',4'-Dihydroxyacetophenone (4-Acetocatechol)   (HMDB0029661, CAS 1197-09-7)
    24. 4-Methylcatechol  (HMDB0000873, CAS 452-86-8)
    25. 2,6-Dimethoxybenzoic acid  (HMDB0029273, CAS 1466-76-8)
    26. Acetylphloroglucinol  (HMDB0029644, CAS 480-66-0)
    27. Salicylic Acid  (HMDB0001895, CAS 69-72-7)
    28. trans-2-Hydroxycinnamic acid  (HMDB0002641, CAS 614-60-8)
    29. Caffeic acid dimethyl ether 3,4-Dimethoxycinnamic acid  (HMDB0034315, CAS 2316-26-9)
    30. 3-Methoxyhydrocinnamic acid  (HMDB0011751, CAS 10516-71-9)
    31. Gallic acid  (HMDB0005807, CAS 149-91-7)
    32. 3,5-Dihydroxybenzoic acid  (HMDB0013677, CAS 99-10-5)
    33. Terephthalic acid  (HMDB0002428, CAS 100-21-0)
    34. Vanillic acid  (HMDB0000484, CAS 121-34-6)
    35. Nordihydroguaiaretic Acid  (HMDB0014325, CAS 500-38-9)
    36. Veratric acid  (HMDB0059763, CAS 93-07-2)
    37. 4-Acetylresorcinol  (HMDB0029657, CAS 89-84-9)
    38. Rosmarinic acid  (HMDB0003572, CAS 20283-92-5)
    39. Hydrocinnamic acid  (HMDB0000764, CAS 501-52-0)
    40. Caffeic acid phenethyl ester  (PUBCHEMCID5281787, CAS 104594-70-9)
    41. 2,3,4-Trihydroxybenzoic acid  (HMDB0059964, CAS 610-02-6)
    42. 2,4-Dihydroxybenzoic Acid  (HMDB0029666, CAS 89-86-1)
    43. 3-Hydroxybenzoic acid  (HMDB0002466, CAS 99-06-9)
    44. Coniferyl Alcohol  (HMDB0012915, CAS 458-35-5)
    45. Sinapyl Alcohol  (HMDB0013070, CAS 0647457-9)
    46. m-Coumaric acid  (HMDB0001713, CAS 14755-02-3)
    47. 2-Acetylresorcinol  (HMDB0029660, CAS 699-83-2)
    48. 4-Methylsyringol  (HMDB0029680, CAS 1730647)
    49. 3,4,5-Trimethoxycinnamic acid  (HMDB0002511, CAS 90-50-6)
    50. α-Methyl-cinnamic acid  (PUBCHEMCID637817, CAS 1199-77-5)

  • Additional information available

    Additional information including additional methods, retention times, m/z transition ions, metabolite annotations, CoA, SDS, etc., are available at or by scanning the QR code on your product.

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