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Polyphenols: Phenolic Acids and Alcohols Standard Mixture

Standard mixture solution for chromatography and mass spectrometry

Tags: polyphenols standard mixt, phenolic acids standard mix, phenolic alcohols standard mix


Use: Liquid Chromatography (LC, HPLC, UHPLC) 

Use: Compounds identification, MS2 transitions,  retention time acquisition, in-house digital library, method development


Suitable for:  LCMS, UHPLC, LCMS, LC-MS/MS, LC-QTOF 

Suitable for: Single quadrupole MS, triple quadrupole MS (QQQ), QTOF, Orbitrap

Suitable: Human metabolomics, plant metabolomics, foodomics, food analysis, volatilomics, cannabis and vape analysis, wine and beer analysis




-Find the retention time of the molecules after changing the method
-Find the retention time of molecules after changing the column
-Use the standards to make calibration curves for quantification


HPLC-MS (single qaud):
-Find the retention time of molecules after changing the method
-Add the compounds to your in-house library for enhanced compound search/identification with RT and M/z value


HPLC-MS/MS (triple qaud):
-Acquire and optimize the transition ions for each molecule using your instrument specific settings
-Use the standards to make calibration curves for quantification


-Use the standards to make calibration curves for quantification
-Add the compounds to your in-house library for enhanced search with RT and M/z value


The presence of polyphenolic micronutrients in food is shown to be beneficial to humans health due to their powerful anti-oxidation properties. MetaSci’s Phenolic Acids and Alcohols (PAA) Standard Mix contains 50 phenolic compounds that are building blocks of polyphenols. The standard mixtures come as 1.0 mM methanolic solution and are suitable to use with HPLC methods utilizing a standard C18 column and MS, UV or ELSD detector. Each mixture is designed to have 9-10 compounds highly resolved on C18 column with no isobaric interference which makes it to work even on a low resolution MS. The standard mixtures can be used for peak identification, making calibration curves for quantification and making an in-house digital library of spectra.

  • 50 phenolic acids and phenolic alcohols, high purity, single peak, completely resolved
  • Fully quantitative, 1mM in MeOH.
  • 5  High recovery sets with 8-12 phenolic compound in each. Each set contains five microampules of 200 uL. Using microampules allows you to keep the unused amount in the sealed glass container. Each set contains 5 microampules, totalling to 25 microampules.
  • Packed under argon
  • Contains an internal standard to adjust your retention time with IS lock
  • No isobaric interference means there are no two compounds with the same molecular formula in a microampule. This design allows identification by low resolution single quad mass spectrometer without a need for digital libraries for identification.

Polyphenols: Phenolic Acids and Alcohols Standard Mixture

  • List of compounds

    1. Pyrogallol (HMDB0013674, CAS 87-66-1)

    2. 2,3-Dihydroxybenzoic acid (HMDB0000397, CAS 303-38-8)

    3. Syringic acid (HMDB0002085, CAS 530-57-4)

    4. Ferulic acid (HMDB0000954, CAS 1135-24-6)

    5. p-Coumaric acid (HMDB0002035, CAS 7400-08-0)

    6. Sinapic acid (HMDB0032616, CAS 530-59-6)

    7. Resveratrol (HMDB0003747, CAS 501-36-0)

    8. trans-Cinnamic acid (HMDB0000930, CAS 140-10-3)

    9. Phloroglucinol (HMDB0013675, CAS 108-73-6)

    10. Resorcinol (HMDB0032037, CAS 108-46-3)

    11. 2,6-Dihydroxybenzoic acid (HMDB0013676, CAS 303-07-1)

    12. Caffeic acid (HMDB0001964, CAS 331-39-5)

    13. Hydroferulic acid (HMDB0062121, CAS 1135-23-5)

    14. Chlorogenic acid (HMDB0003164, CAS 327-97-9)

    15. Syringol (HMDB0034157, CAS 91-10-1)

    16. 4-Methylguaiacol (HMDB0032136, CAS 93-51-6)

    17. 4-Ethylphenol (HMDB0029306, CAS 123-07-9)

    18. Nordihydroguaiaretic Acid (HMDB0014325, CAS 500-38-9)

    19. 3,4-Dihydroxybenzoic acid (HMDB0001856, CAS 99-50-3)

    20. Catechol (HMDB0000957, CAS 120-80-9)

    21. 4-Acetocatechol (HMDB0029661, CAS 1197-09-7)

    22. 4-Methylcatechol (HMDB0000873, CAS 452-86-8)

    23. Acetylphloroglucinol (HMDB0029644, CAS 480-66-0)

    24. 4-Hydroxybenzoic acid (HMDB0000500, CAS 99-96-7)

    25. Homovanillic acid (HMDB0000118, CAS 306-08-1)

    26. Caffeic acid dimethyl ether (HMDB0034315, CAS 2316-26-9)

    27. 3-Methoxyhydrocinnamic acid (HMDB0011751, CAS 10516-71-9)

    28. 4-Ethylguaiacol (HMDB0040175, CAS 2785-89-9)

    29. 4-n-propylphenol (HMDB0032625, CAS 645-56-7)

    30. Caffeic acid phenethyl ester (PUBCHEMCID5281787, CAS 104594-70-9)

    31. Gallic acid (HMDB0005807, CAS 149-91-7)

    32. 3,5-Dihydroxybenzoic acid (HMDB0013677, CAS 99-10-5)

    33. Tyrosol (HMDB0004284, CAS 501-94-0)

    34. Dihydrocaffeic acid (HMDB0000423, CAS 1078-61-1)

    35. Vanillic acid (HMDB0000484, CAS 121-34-6)

    36. 4-Acetylresorcinol (HMDB0029657, CAS 89-84-9)

    37. 3,5-Dimethoxyphenol (HMDB0059966, CAS 500-99-2)

    38. Hydrocinnamic acid (HMDB0000764, CAS 501-52-0)

    39. Salicylic Acid (HMDB0001895, CAS 69-72-7)

    40. 2,3,4-Trihydroxybenzoic acid (HMDB0059964, CAS 610-02-6)

    41. 2,4-Dihydroxybenzoic Acid (HMDB0029666, CAS 89-86-1)

    42. 3-Hydroxybenzoic acid (HMDB0002466, CAS 99-06-9)

    43. phenol (HMDB0000228, CAS 108-95-2)

    44. Coniferyl Alcohol (HMDB0012915, CAS 458-35-5)

    45. m-Coumaric acid (HMDB0001713, CAS 14755-02-3)

    46. 2-Acetylresorcinol (HMDB0029660, CAS 699-83-2)

    47. 4-Methylsyringol (HMDB0029680, CAS [6638-05-7)

    48. 3,4,5-Trimethoxycinnamic acid (HMDB0002511, CAS 90-50-6)

    49. α-Methyl-cinnamic acid (PUBCHEMCID637817, CAS 1199-77-5)

    50. trans-Pterostilbene (HMDB0130987, CAS 537-42-8)

  • Additional information available

    Additional information including methods, retention times, m/z transition ions, metabolite annotations, CoA, SDS, etc., are available at or by scanning the QR code on your product.

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